Landmark 81/100
Dietary acid load and CKD progression
In plain English
Higher dietary acid load (typical of animal-protein-heavy diets) was associated with faster progression to end-stage renal disease in adults with CKD. Plant-based diets generate less acid that the kidney must excrete, plausibly preserving function.
Why it matters
Higher dietary acid load → faster CKD progression.
Informs: Kidney Disease
Provenance
- Design
- Prospective cohort
- Sample size (n)
- 1,486
- Follow-up
- 14 years
- Peer-reviewed
- Yes
- Replications
- 2
- Funding
- Public / academic
- Funders
- US NIH (NIDDK)
- Institutions
- University of California San Francisco, Johns Hopkins
decades.plus score
A transparent 0–100 weighted sum across six components. Higher scores reflect bigger, cleaner, more replicated work.
Landmark 81/100
Caveats
Dietary acid load is calculated, not measured, from food-frequency data. Mechanism is well-established but absolute effect varies with baseline kidney function.
