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Landmark 82/100

Plant protein intake and all-cause mortality in chronic kidney disease — NHANES III

In plain English

Using national NHANES data on 14,866 American adults — including 1,065 with reduced kidney function — researchers tested whether the source of dietary protein matters. Among people with chronic kidney disease (eGFR below 60), each 33% increase in the share of protein coming from plants was associated with 23% lower all-cause mortality. No such benefit appeared in those with healthy kidneys, suggesting plant protein matters most once the kidneys are already stressed.

Why it matters

In CKD, each 33% rise in plant-protein share was linked to 23% lower mortality.

Informs: Kidney Disease

Provenance

Design
Prospective cohort
Sample size (n)
14,866
Follow-up
14 years
Peer-reviewed
Yes
Replications
1
Funding
Public / academic
Funders
US National Institutes of Health, US Department of Veterans Affairs
Institutions
University of Utah, Salt Lake City VA Health Care System

decades.plus score

A transparent 0–100 weighted sum across six components. Higher scores reflect bigger, cleaner, more replicated work.

Landmark 82/100
  • Study design 20/25
  • Sample size 15/20
  • Funding independence 20/20
  • Journal + peer review 15/15
  • Institution tier 6/10
  • Replication 6/10

Caveats

Observational; protein source correlates with overall diet quality and lifestyle. It rests on a single baseline dietary recall, and the CKD subgroup (n=1,065) is modest, which widens the confidence interval.