DiRECT — Primary care-led weight-management for remission of type 2 diabetes
In plain English
British family practices delivered a structured, calorie-restricted whole-food programme to adults with type 2 diabetes of <6 years duration. 46% of the intervention group were in clinical remission at one year, versus 4% of controls — the first time diet-led remission of T2D was demonstrated at scale inside a national primary care system.
Why it matters
46% of T2D patients achieved remission at 1 year on a structured whole-food programme.
Informs: Weight Loss·Diabetes
Provenance
- Design
- Randomised controlled trial
- Sample size (n)
- 306
- Follow-up
- 2 years
- Peer-reviewed
- Yes
- Replications
- 2
- Funding
- Public / academic
- Funders
- Diabetes UK
- Institutions
- University of Glasgow, Newcastle University, NHS Scotland
decades.plus score
A transparent 0–100 weighted sum across six components. Higher scores reflect bigger, cleaner, more replicated work.
Caveats
Restricted to early-stage T2D (<6 years). Remission rates fell at 2-year follow-up; long-term maintenance is the harder challenge.