Strong 78/100
INTERSTROKE — Global and regional effects of potentially modifiable risk factors for stroke
In plain English
A 32-country case-control study of nearly 27,000 first-stroke patients and matched controls. Ten modifiable factors — chiefly hypertension, but also diet, exercise, smoking, alcohol, lipids and stress — collectively accounted for about 90% of stroke risk worldwide.
Why it matters
10 modifiable factors explain 90% of stroke risk globally.
Informs: Stroke
Provenance
- Design
- Case-control
- Sample size (n)
- 26,919
- Peer-reviewed
- Yes
- Replications
- 1
- Funding
- Public / academic
- Funders
- Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada
- Institutions
- McMaster University, Population Health Research Institute
decades.plus score
A transparent 0–100 weighted sum across six components. Higher scores reflect bigger, cleaner, more replicated work.
Strong 78/100
Caveats
Case-control design recalls exposure after the event, which can bias self-report. The 90% population-attributable risk depends on assumptions about exposure prevalence.
