Alzheimer's now kills more Americans than breast and prostate cancer combined. Mounting evidence reframes it as a metabolic disease — insulin resistance in the brain — putting diet front and center. The Mediterranean and MIND diets are the only interventions that have shown consistent risk reductions in large prospective cohorts.
High adherence: 53% lower Alzheimer's risk over 4.5 yrs.
Mediterranean-style diet → 35% lower dementia risk.
Diet + exercise + cognitive training preserved cognition in at-risk adults.
Meat-eaters had 2× the dementia risk of vegetarians.
Insulin resistance, oxidative stress, and chronic inflammation in the brain converge on amyloid and tau pathology. Diets high in saturated fat and refined carbs accelerate all three. Green leafy vegetables, berries, nuts, olive oil and omega-3s consistently reverse the trajectory in observational and trial data.
"What's good for the heart is good for the brain." — every Alzheimer's neurologist, eventually.